BDBM445212 US10669235, Example 3::US11208381, Example 3

SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC3CCN(C)CC3)c3ccccc3)c2cc1C

InChI Key InChIKey=UKGLXBBBCMZJSW-ZIADKAODSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445212   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
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US Patent
LigandPNGBDBM445212(US10669235, Example 3 | US11208381, Example 3)
Affinity DataKi:  73.1nMAssay Description:The inhibitory activities of compounds of the invention against VEGFR1 (VEGFR1 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR1 pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Respivert

US Patent
LigandPNGBDBM445212(US10669235, Example 3 | US11208381, Example 3)
Affinity DataKi:  73.1nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA, 1 mM DTT and 2 mM MnCl2. The inhibitory activities of compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent